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(2003) found that hypothyroidism caused oxidative stress in the liver and heart, causing an imbalance between ROS and endogenous antioxidant body defenses, with subsequent damage to cellular macromolecules ( L-thyroxine administration moderated such oxidative stress in hypothyroid rats through normalizing the plasma MDA level and plasma TAC, in agreement with Varghese et al

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Independent third-party testing confirms purity exceeds 99% for each batch not as a target, but as a minimum standard