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Specifically, nhr-49 is required to induce several fatty acid -oxidation genes in long-lived glp-1 mutants (Ratnappan et al., 2014)

10.3390/nu12092645 62

Moreover, in the skeletal muscles of AX-treated obese and lean mice, the expression levels of Sirtuins, such as Sirt1 and Sirt3, were upregulated (Figure 2)

Gadaleta, V

Specifically, rme-2 (RNAi) animals showed an approximately 45% increase in total lipid content such that the gonad-to-somatic ratio was roughly 30% lower compared with controls
