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compared administration of ALC versus a placebo in 102 FMS patients according to the 1990 ACR criteria

In addition, other studies have also demonstrated the involvement of TRP channels in paclitaxel-induced pain, which are well known to be predominantly expressed on this subpopulation of DRG neurons

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The findings of the literature review suggested that H 2 exerts anti-fatigue effects, and that these effects may involve not only the direct scavenging of mitochondria-generated ROS by H 2 , but also its antioxidant and anti-inflammatory effects through the regulation of gene expression (31, 46, 50)

However, the underlying mechanism remains unclear