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Here the authors engineered a probiotic to tolerate oxidative stress, an alleviate type 2 diabetes in mice by activating host metabolic pathways.

Currently, the treatment of the disease is restricted to controlling symptoms and, more recently, a group of drugs that act directly on the defective protein, known as CFTR modulators, was developed

First described in the mid-1990s, it is classified as a growth hormone secretagogue (GHS), a category of compounds designed to interact with the ghrelin/GHS receptor