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Alternative treatments may include: Physical therapy Using assistive devices like canes or walkers Nutritional changes to remove inflammatory foods from your diet Weightloss if obesity is a factor Modifying daily activities to reduce stress on your joints Low-impact exercises, such as water aerobics or gentle chair yoga For most people with osteoarthritis, you will eventually require to replace your knee

10.1016/j.celrep.2021.109960 131 XuB.WangZ.LiG.LiB.LinH.ZhengR.et al (2006)

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Pickart (2008) reviewed the broader tissue remodeling context and argued that GHK operates as a damage signal released from injured or aging tissue, recruiting repair processes that decline as the signal itself becomes less abundant