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Besides its role in long- and medium-chain fatty acid transport and oxidation, carnitine is essential for regulating the availability of nonesterified CoA within the mitochondrial matrix and serves as a reservoir for excess acetyl groups produced during fatty acid and pyruvate oxidation

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Der Stoff verbessert die Insulinsensitivitt der Zellen (3) und wirkt daher der fr Diabetes Typ 2 typischen Insulinresistenz entgegen

Due to the lack of carnitine in many parenteral solutions and the increased metabolic demands, these patients may experience decreased mitochondrial function, muscle weakness, and metabolic disturbances