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doi: 10.1080/15412555.2017.1347918
RIP1 and RIP3 form heterodimeric scaffolds in the complex, and while RIP1RIP1 interactions are dispensable for necroptosis, RIP1RIP3 or RIP3RIP3 interactions are required for induction of necroptosis100
Do not stop prescribed B12 supplementation without consulting your GP, as untreated deficiency can cause serious neurological harm
