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Fidler found that besides mechanical attract of traveling tumor cells in the capillary bed of distant organs, specific cells residing the metastatic organs played essential roles in the subsequent cancer cell proliferation in the secondary lesions during the colonization process using B16 melanoma as the cancer model [23]

Polysaccharides exhibit virous pharmacological properties including hypoglycemic, hypolipidemic, immunomodulatory, and anti-tumor effects

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Funding This work was supported by the: Parkinson Research Consortium of Ottawa (J.M.T., D.N.E.K., T.K.F., J.J.T., A.C.)