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Description
Reported biochemical potency against human NNMT is in the low-micromolar range with cellular EC values in the low-micromolar range for suppression of 1-MNA and lipogenesis, with selectivity over related methyltransferases and NAD-salvage enzymes [1,6,7]
This improvement in strength was accompanied by enhanced muscle endurance and accelerated recovery from muscle injury, indicating comprehensive restoration of muscle function rather than isolated effects
Heavier individuals with more adipose tissue often benefit from doses at the higher end of the standard range (450-500mcg)

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