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Methods for transplantation of human cerebral organoids into the adult mouse brain have been established, and organoids demonstrate neuronal differentiation, axonal pathfinding, and integration with host neuronal circuits in the brains of normal and neonatal thymus-less rats, which represent important research advances in the integration of cerebral organoids with neural circuitry in the host brain [12] (Fig

However, recently, it was found that the driving pressure and RR components of MP were the best predictors of mortality

Ramires Jnior OV, et al

The trial did not meet its efficacy endpoint, but tolerability was not the reason the program was discontinued

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