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If symptoms are coming back before your next jab is due, this would point to you not having them often enough to stay stable symptom wise
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In addition, the recommended phase II dose was established as 10 mg twice a day
Wang W, Liu G, Zheng J
Postoperative chemotherapy use after neoadjuvant chemoradiotherapy for rectal cancer: Analysis of Surveillance, Epidemiology, and End Results-Medicare data, 1998-2007
