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[ref] The rare mutations that cause early-onset Alzheimers cause the astrocytes to have reduced expression of EAAT2.[ref] The rare mutations in the LRRK2 gene that cause familial Parkinsons also interact with EAAT2 expression in glial cells.[ref] Related article : APOE and Alzheimers disease | Parkinsons genetic susceptibility Epilepsy: The glutamate transporters are responsible for keeping glutamate low, and thus, they play an important role in epilepsy

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SARS-CoV-2 potentiates all three components of Virchows triadhypercoagulability, blood flow stasis, and endothelial cell damageto increase risk of thrombosis [43]