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This condition follows an autosomal recessive pattern, impacting approximately 1 in every 30,000 individuals [121]

Recently, induction of PGHS-2 has been also linked with seizures and PGHS-2 inhibitors have been proposed as potential therapeutic option, targeting PGHS-2 mediated neuroinflammation during epilepsy [73]

547 Various laboratory techniques, such as polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP), allele-specific oligonucleotide polymerase chain reaction (ASO-PCR), single-strand conformation polymorphism (SSCP), long-range PCR, and Southern blot, have traditionally been used to screen for point mutations and deletions in mtDNA

Encourages collagen and elastin synthesis to improve firmness, elasticity, and overall skin structure

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