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There was also no significant difference found in the secondary outcome of general distribution of specific hangover symptoms including headache with NAC and Placebo both with median = 1 ( P = 0.93), nausea with median score for NAC = 0, and Placebo = 1 ( P = 0.11), and weakness with NAC median = 1, and Placebo median = 1 ( P = 0.72)

One promising option for symptom management is IV therapy, specifically the Myers Drip

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Progress to activity-specific movements at reduced intensity

doi: 10.1016/j.jnutbio.2020.108431