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Recent research also suggests that abnormalities in tau proteins are a potential cause of familial Parkinsonism and frontotemporal dementia
Placebo-controlled studies have shown that VIC can reduce the severity and duration of symptoms, with some reporting a reduction of as little as 5% in some cases and others reporting a reduction of 50%
85 However, the inhibition of MLCK is not clinically feasible due to the associated severe toxicity

Riboflavin may be able to decrease the number of migraine headaches a person has
10.1371/journal.pone.0164678 PLoS One 143 ShahD