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Hepatology 47: 511520 Lin CP, Liu CR, Lee CN, Chan TS, Liu HE (2010) Targeting cMyc as a novel approach for hepatocellular carcinoma

Biomed Pharmacother 111:802812

1 were formulated in the standard way assuming mass action kinetics for the various reaction steps

An alternative approach escalates both agents simultaneously but at slower intervals, extending the total escalation period to twenty weeks or longer

& Bryce, P
