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Results announced in October 2025 demonstrated orforglipron's superiority on both HbA1c and weight endpoints, positioning it as a more effective second-line oral agent than existing oral diabetes medications

All images were processed in the Imaging Core Facility, at Yale University

ORF3a-GFP and its mutants were generated by cloning ORF3a into an in-house modified version of pLVX-EF1alpha-GFP vector

Therefore, the homeostasis of renal energy metabolism, especially fatty acid metabolism, serves as an essential material basis for maintaining normal qi transformation and preventing internal generation of dampness-turbidity

Bechmann, L