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While such evidence supports further exploration of Lion's mane as a complementary approach for cognitive decline, it should be noted that there was a decline in cognitive improvements after 4 weeks, suggesting that continuous intake of Lion's mane may be necessary to maintain its benefits

[8] Moreover, the research team suggested that the peptide may have facilitated the recovery of blood flow in the ischemic muscle of the rat hind limb, as determined by laser Doppler scanning, indicating the compounds potential to promote angiogenesis

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