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Functional medicine is a healthcare model that views the individual patient as a separate entity

Free Rad Res 54(1):126 Chen W-J, Lin K-H, Lee Y-S (2000) Molecular characterization of myocardial fibrosis during hypothyroidism: evidence for negative regulation of the pro-1 (I) collagen gene expression by thyroid hormone receptor

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Whether this decline is a cause or consequence of aging and disease remains an active area of research