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For example, a patient who does not present in DKA and has a lower HbA1c ( 10%, we will assume he is a bit more insulin resistant, so we will use the upper end of this range, thus TDD of 0.6 u/kg/day TDD * weight (in kg) = total units of insulin per day 0.6 u/kg/day * 17 kg = 10.2 units/day A 14-year-old, non-obese (59 kg), pubertal female presents with hyperglycemia, HbA1c 9%, and has suspected T1DM based on second-tier laboratory testing

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Why study dosing is not a personal dose A study dose answers a research question

Can tirzepatide cause serious heart rhythm problems? Tirzepatide does not increase the risk of serious arrhythmias, myocardial infarction, or sudden cardiac death in patients without pre-existing cardiac disease