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Our data, consistent with the literature [32], show that chronic duration of therapy, higher cumulative metformin dose and concomitant PPI therapy (Table 1) increase the risk of vitamin B 12 deficiency

Biotin Caution With Lab & At-Home Tests June 02, 2023 High doses of biotin from supplements can interfere with a wide range of laboratory and at-home tests, including those for pregnancy, doping, COVID, and heart attacks

Knowing your body's capability and constantly challenging yourself I find is the key
