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Description
Functionally, L5p neurons can be divided into three compartments: (1) a basal compartment (soma-proximal dendrites), (2) an apical compartment (tuft dendrites), and (3) a coupling compartment (apical trunk and oblique dendrites) (Aru et al., 2020

10.1089/jicm.2023.0315 50 LiL.ZhuW.LinG.ChenC.TangD.LinS.et al (2022)

The most common deficient variant is G6PD A

GSH is often referred to as the major antioxidant of the cell, though the functions of GSH extend beyond its antioxidant properties to many other essential cellular processes, including detoxification of xenobiotic compounds, modulation of cell proliferation, transport and storage of cysteine and maintenance of redox status [[14], [15], [16], [17]]

Increased glutamate release leads to motor neuron hyperexcitability, aberrant firing, increased intracellular calcium, and cell death [312]
