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The enzyme beta-secretase cleaves APP to produce A peptides, particularly A42, which aggregate into toxic oligomers that form plaques

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In addition, high levels of HO-1 have been observed in various human solid tumors, such as renal [87], prostatic [88], and pancreatic cancers [89]

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Glutathione and ROS staining of primary T and B cells Glutathione and ROS staining of human T and B cells was performed on freshly isolated mononuclear cells from peripheral blood or bone marrow samples from 7 control donors and 17 patients

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