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Several approaches have been developed to access pH at injury sites, including materials integrated with pH sensors [349], wound dressings mixed with pH-indicating dyes [350], and pH-sensitive fluorescent probes [351]

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Topical: This involves applying the AHK-Cu solution directly to a surface

Thus, the demonstrated leading role of the rapid heart disturbances and general vascular failure in the major vessels-induced occlusive syndromes [14,15,16,17,18,19,20], severe intoxication (i.e., alcohol, lithium) [21,22] and maintained intra-abdominal hypertension [23] suggest that an application of isoprenaline by its own can induce rapidly its own occlusion-like-syndrome, an early disturbance decisive for further isoprenaline-myocardial lesion progression