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Combining both GPX4 inhibitors at 500 nM triggered fer-1-suppressible cell death with similar kinetics to either GPX4 inhibitor alone, indicating this was a saturating dose of inhibitor (Fig

[DOI] [PMC free article] [PubMed] [Google Scholar] 74.Lee Y, Lee Y, Kim S, Kim S, Yoo S

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Many of these reactions generate free radicals that can, if not controlled (neutralized), cause damage inside your body (oxidative stress)

Thiol-disulfide exchange in signaling: disulfide bonds as a switch
