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The histopathological hallmark of the cuprizone model as standardized by Hiremath is oligodendrocyte death and subsequent demyelination in the corpus callosum, superior cerebellar peduncles, hippocampus [42, 46,47,48,49,50,51,52,53,54] and several other areas of the mouse brain (reviewed in [20])

If you feel sad, depressed and hopeless, suicidal thoughts may follow

Teng Xu and colleagues identified that, in head and neck squamous cell carcinoma (HNSCC), the DLG motif within tumor necrosis factor--induced protein 2 (TNFAIP2) competes with the Kelch domain of Keap1, thereby inhibiting the ubiquitin-proteasome-mediated degradation of NRF2

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doi: 10.1007/s10072-020-04957-7 201 OhgamiR