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Many probiotics exhibit BSH activity, deconjugating primary BAs, which is a critical upstream step influencing the availability of substrates for secondary BA synthesis and modulating FXR signaling (147)

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Food-derived and natural bioactive compounds-particularly those that can be realistically incorporated into dietary patterns-have emerged as promising adjunctive strategies for promoting stroke recovery, owing to their capacity to modulate key biological processes involved in neurorepair

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