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10.1046/j.1432-1327.2000.01828.x [DOI] [PubMed] [Google Scholar] Jafarzadeh Bejargafshe M., Hedayati M., Zahabiasli S., Tahmasbpour E., Rahmanzadeh S., Nejad-Moghaddam A

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Higher delta activity during this phase is considered an indicator of increased sleep quality, according to research [2]

Notably, both MG and 7-HMG display G proteinbiased agonism at MOR, preferentially activating G-protein pathways over -arrestin recruitment, a signaling profile that has been hypothesized to underlie improved therapeutic outcomes (Kruegel et al., 2016