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Whitehead M, Osborne A, Widdowson PS et al (2019) Angiopoietins in diabetic retinopathy: current understanding and therapeutic potential
Diclofenac which is a proven, nonsteroidal anti-imflammatory drug (NSAID) is used mostly in human medicine to treat a variety of acute and chronic pain and inflammatory conditions via inhibition of prostaglandin synthesis by inhibiting cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) Gan,2010
Spermine catabolism can also be accomplished by its conversion back to spermidine via the activity of the SMOX (spermine oxidase) encoded FAD-dependent enzyme
Rab4A-directed endosome traffic shapes pro-inflammatory mitochondrial metabolism in T cells via mitophagy, CD98 expression, and kynurenine-sensitive mTOR activation
One patient had life-threatening sepsis related to a Portacath device placed for rituximab but had good response to immunotherapy
