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[DOI] [PubMed] [Google Scholar] 30.Ikemoto K., Mohamad Ishak N.S., Akagawa M

Bpy is extensively used as the core structure of many chelating ligands by acting as a bridge in the arrangement of the catalytic center

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Preclinically, these inhibitors reduce infarct volumes and improve functional recovery, not merely by lowering lactate but by reprogramming cellular metabolism: forcing neurons to resurrect oxidative phosphorylation in salvageable penumbral regions and redirecting glucose toward the PPP to bolster NADPH-dependent antioxidant defenses [208, 209]