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ARA 290 improves symptoms in patients with sarcoidosis-associated small nerve fiber loss and increases corneal nerve fiber density

[DOI] [PMC free article] [PubMed] [Google Scholar] 450.McNeilly S, Thomson CR, Gonzalez-Trueba L, Sin YY, Granata A, Hamilton G, Lee M, Boland E, McClure JD, Lumbreras-Perales C, Aman A, Kumar AA, Cantini M, Gk C, Graham D, Tomono Y, Anderson CD, Lu Y, Smith C, Markus HS, Abramowicz M, Vilain C, Al-Shahi Salman R, Salmeron-Sanchez M, Hainsworth AH, Fuller W, Kadler KE, Bulleid NJ, Van Agtmael T

Critical points are represented by the actual relevance of the mucus layer covering the epithelium of the nasopharynx, by the interaction of the meningococcus with the different cell types of the human nasopharynx and the local microbiota, and by the mechanism of invasion of the epithelium (intracellular or paracellular)