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Model 3 was adjusted comprehensively to include chronic comorbidities (hypertension, coronary heart disease, stroke, and diabetes) based on Model 2
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39,40 GIP retains also the ability to stimulate glucagon secretion in people with T2DM and unlike what is reported in healthy people, subjects with T2DM demonstrate increased glucagon secretion in response to GIP during hyperglycemia
Bilkei-Gorzo et al., 2017
