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P.) 729, 157179 (Springer US, New York, NY, 2012)

Activation of mTOR in Alzheimers disease Insulin resistance or impaired insulin sensitivity is typical in AD and can be developed by activation of the mTOR (mammalian target of rapamycin) (Arnold et al

This mutation leads to detrimental phenotypes such as premature aging, senescence, immune deficiency, and neurodegeneration 111,288

In the context of the immune system, optimal glutathione levels are essential for the maintenance of a redox-balanced environment for the proper functioning of lymphocytes and macrophages [6,7]

doi:10.1126/science.1235122
