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(2001) 280:E2218

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However, it remains unapproved by the FDA and banned for human use in many countries due to the lack of human trials and concerns over safety, contamination, and legal misuse

During the early stages of acute pancreatitis, the inflammatory response damages the intestinal barrier, allowing bacteria and endotoxins to enter the blood, triggering an inflammatory storm, sepsis, and even multiple organ failure [92]
