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Studies suggest injection of botulinum toxin, a neurotoxin secreted by the bacterium Clostridium botulinum , to sites of painful diabetic neuropathy may significantly reduce pain and improve sleep quality
doi: 10.1016/0891-5849(93)90171-p
doi:10.1001/jama.279.15.1200 [DOI] [PubMed] [Google Scholar] 10.Dwyer JT, Coates PM, Smith MJ
2011, Schnemann et al
Injections deliver the full dose directly for immediate bioavailability
