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additionally, alcar raised the transcription of grm2 gene encoding for the mglu2 receptor via increasing the levels of acetylated h3k27 bound to the grm2 promoter and gaining the acetylation of nf-kb-p65 subunit

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An FXR knockout mouse model resulted in glucose intolerance and insulin insensitivity (280)

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[DOI] [PubMed] [Google Scholar] 66.Trapp B.D., Peterson J., Ransohoff R.M., Rudick R., Mrk S., B L