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This reaction is all thanks to a specific gene variant that makes it incredibly tough for your body to break down a toxic byproduct of alcohol called acetaldehyde

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Neurochem Int 51:361369 Liu G-H, Qu J, Suzuki K, Nivet E, Li M, Montserrat N, Yi F, Xu X, Ruiz S, Zhang W et al (2012) Progressive degeneration of human neural stem cells caused by pathogenic LRRK2

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Soon after the revenuers had arrived, the ships were often visited by merchants looking for first choice on the arriving goods