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Zozina et al
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Norepinephrine not only has neuroprotective and anti-inflammatory effects, but also can promote the differentiation of oligodendrocytes, and then promote the formation of myelin (Galea et al
The logic is that sustained exposure over a longer window may matter more than peak concentration particularly for an epigenetic mechanism that operates through gene expression changes, which take time to manifest
doi: 10.1093/jn/133.2.381
