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A Phase 1 clinical trial was started in 2012 and then quietly discontinued
[DOI] [PubMed] [Google Scholar] 57.Weiss KH, Thurik F, Gotthardt DN, Schafer M, Teufel U, Wiegand F, et al
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The recycling reaction was initiated by the addition of reaction buffer (100 mM sodium phosphate, pH 7.4), supplemented with 5,5-dithiobis (2-nitrobenzoic acid) (DTNB) (100 M) (Sigma), NADPH (100 M) (Roth), glutathione reductase (1 U/ml) (Sigma), and EDTA (1 mM) (Sigma)
Endothelial Nitric Oxide Synthase (eNOS) and the Cardiovascular System: in Physiology and in Disease States
