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Description
The suggestion that carnitine deficiency may lead to frailty through mitochondrial dysfunction (117) has been examined in one trial

This reaction is a rate-controlling step for the -oxidation of fatty acid (13)

die Skelett- und Herzmuskulatur

It is postulated that clinical symptoms, including CNS complications such as convulsion, coma and lethargy, may be triggered by the accumulation of metabolites and their acyl-CoA derivatives that disrupt intermediary metabolism [6669]
Isidori, A
