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Ethics approval and consent to participate statement All methods were performed in accordance with the relevant guidelines and regulations and all procedures involving animal research were approved by the Animal Care and Use Committee of the University of Western Ontario (Protocol number: 2022-119)

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Florance I, Ramasubbu S

d, Western blot showing NRF2 pathway activation of H358 cells with KEAP1 deletion at the basal state

The North American Menopause Society (NAMS, 2022) and ACOG now recognize that for healthy women under 60 particularly within 10 years of menopause HRT may offer protective effects for bone, heart, and cognitive health, beyond symptom relief
