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In one study involving diabetes patients with neuropathic ulcers, GHK-Cu gel significantly improved the rate of ulcer healing and reduced the incidence of infection [11]

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Risk-of-bias reduction strategies such as robust randomization methods, allocation concealment, blinding of outcome assessors, and intention-to-treat analysis should be incorporated to improve internal validity and reproducibility

Notably, MCT1 blockade in HCC cells promotes ferroptosis without observable alterations in GPX4 and FSP1 expression levels, while lactate uptake in melanoma cells via MCT1 elevates NADH, NADPH, GPX4 and FSP1