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As reported by Doate-Buenda et

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To avoid side reactions with imide nitrogen, it is crucial to choose an appropriate base (e.g., sodium bicarbonate, sodium carbonate) 117

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In the neuroblastomaglioma (NG108-15) hybrid cells, morphine pretreatment failed to promote uncoupling of DOR from G proteins while methadone did (Liu et al., 1999b)

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