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(iii) disruption of metabolic support of neurones and oligodendrocytes 147,148
The most characterized lysosomal sorting pathway for GPCRs involves the ubiquitin-dependent endosomal-sorting complex required for transport machinery (ESCRT) (Bao et al., 2020)

VaccarinoVShahAJMehtaPKPearceBRaggiPBremnerJDet alBrain-heart connections in stress and cardiovascular disease: implications for the cardiac patient

Schlosser S, Azzaroli F, Dao T, Hingorani R, Crispe I, Boyer J

Elevated IL-1 mRNA expression occurs within the first 15-30 min after permanent MCAO and elevated IL-1 protein expression occurs a few hours later and remains elevated for up to 4 days [32]
