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In a 2019 study published in NCBI, titled "The Role of Vitamins and Minerals in Hair Loss: A Review," researchers stated that "vitamin B12 [is one] of the vitamins and minerals that may be involved in hair graying/whitening during childhood or early adulthood

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These can include: learning problems or intellectual disabilities delays in walking and motor skills abnormal involuntary movements ( dystonia and chorea ) rigid muscle tone, called spasticity poor growth with short stature skin rashes and infections osteoporosis enlarged liver kidney disease or failure vision loss due to problems with the nerves in the eye Without treatment, brain and nerve damage can occur