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FTH neuron-specific knockout (FTH-KO) mice are more susceptible to ferroptosis after TBI, and the absence of FTH offsets the protective effect of melatonin on ferroptosis induced by TBI, 659 suggesting that melatonin plays a protective role at least in part by inhibiting FTH-mediated ferroptosis in neurons after TBI

23 The factors related to epigenetics that contribute to the onset of diseases are extensive

[DOI] [PMC free article] [PubMed] [Google Scholar] 71.Sivick K.E., Mobley H.L.T

To assay the redox properties of purified NERNST, dimers were incubated with 10 mM H 2 O 2 , 10 mM DTT or 0.5 mM of either NADPH, NADH or GSH in 100 mM K 3 PO 4 pH 7