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Curr Med Chem 13:883895
[DOI] [PubMed] [Google Scholar] 19.Staresinic M., Sebecic B., Patrlj L., Jadrijevic S., Suknaic S., Perovic D., Aralica G., Zarkovic N., Borovic S., Srdjak M., et al

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Cell life versus cell longevity: the mysteries surrounding the NAD+ precursor nicotinamide

The mitochondrial workload MOTS-c creates will exhaust available NAD+ faster than baseline metabolism, reducing the magnitude and duration of AMPK's effects
