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Additional indicators of nociplastic pain include extensive healthcare utilization, high levels of pain-related distress, and a family history of chronic pain or psychological disorders
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4,5 Diabetic peripheral neuropathy (DPN), the most common form of DN, is characterized by distal symmetric polyneuropathy, leading to sensory loss, pain, and motor dysfunction in the extremities and is a primary cause of foot ulcers and lower-limb amputations in diabetes patients

101095604, PREVALUNG-EU), the European Research Council (ERC-2021-ADG no

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