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3.1 Age-related macrostructural WM changes A variety of age-related macrostructural WM changes, including reduced WM volume, WM lesions, disrupted WM integrity, and subsequent cortical disconnection have all been observed in normal aging brains (Caligiuri et al., 2015)
Comporti M, Signorini C, Leoncini S, Gardi C, Ciccoli L, Giardini A, Vecchio D, Arezzini B
Targeted Nrf2 may be an effective treatment
CFD has also been described in adults presenting with neurological symptoms (194)
