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doi: 10.1186/s12889-017-4623-y

Meanwhile, the pro-inflammatory state, a result of local oxidative stress, stimulates many cytokines, such as IL-1 and TNF-

Although the exact pathogenesis of PD is still uncertain, it has been reported that mitochondrial dysfunction, oxidative stress, neuroinflammation, and environmental toxins are important factors for the death of DAergic neurons [5, 6]

All the above findings suggest that DKK1 can be used as a biomarker for further clinical decision making for ACS patients

It not only exhibits anti-tumor effects but also enhances chemotherapy sensitivity by regulating tumor vascular function, among other effects (30)